Figure 2 | Scientific Reports

Figure 2

From: Guiding and monitoring focused ultrasound mediated blood–brain barrier opening in rats using power Doppler imaging and passive acoustic mapping

Figure 2

Targeting FUS with microbubble-enhanced power Doppler. (a) Using 8.9 MHz, SVD filtering of B-mode images removed stationary signals in the cellulose tube (red box highlights stationary boundary), and (b) similar SNR was feasible through the skull phantom. (c) In vivo imaging through the skull was performed at 5.2 MHz to account for skull thickness. (d) RCB passive acoustic map overlayed on skull phantom B-Mode image revealed regions undergoing cavitation in the skull phantom. Cavitation energy is contained within the green focus. (e) A \(\overrightarrow {{T_{error\_PAM} }}\) comparison in in vitro cellulose tube and skull phantom, each undergoing 10 trials. (f) The point of maximum intensity in 3 steered maps was calculated and plotted in lateral dimension for cellulose phantom with and without skull.

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