Table 4 Differentially expressed genes of hub genes in U87 glioblastoma cells upon treatment of CCA-1.1.
No | Gene symbol | Ref seq | Gene name | Log FC | p value |
|---|---|---|---|---|---|
1 | EGFR | NM_001346900.2 | Epidermal growth factor receptor (EGFR), transcript variant 8, mRNA | 8.83688311 | 1.03E-05 |
NM_001346941.2 | Epidermal growth factor receptor (EGFR), transcript variant EGFRvIII, mRNA | −6.111141843 | 0.00063995 | ||
NM_001346898.2 | Epidermal growth factor receptor (EGFR), transcript variant 6, mRNA | −2.651710224 | 0.10586144 | ||
NR_047551.1 | EGFR antisense RNA 1 (EGFR-AS1), long non-coding RNA | 2.325569699 | 0.30560263 | ||
NM_201283.2 | Epidermal growth factor receptor (EGFR), transcript variant 3, mRNA | −0.969886184 | 0.5118575 | ||
NM_001346899.2 | Epidermal growth factor receptor (EGFR), transcript variant 7, mRNA | −0.816340926 | 0.56093641 | ||
XM_047419953.1 | Epidermal growth factor receptor (EGFR), transcript variant X2, mRNA | −0.777241106 | 0.59354503 | ||
NM_001346897.2 | Epidermal growth factor receptor (EGFR), transcript variant 5, mRNA | 0.155644698 | 1 | ||
2 | TP53 | not found | Not found | Not found | Not found |
3 | AKT1 | NM_001014431.2 | AKT serine/threonine kinase 1 (AKT1), transcript variant 3, mRNA | −0.173979481 | 0.8970585 |
4 | ALB | not found | Not found | Not found | Not found |
5 | SRC | not found | Not found | Not found | Not found |
6 | TNF | NM_016292.3 | TNF receptor associated protein 1 (TRAP1), transcript variant 1, mRNA; nuclear gene for mitochondrial product | 0.095069258 | 0.94426958 |
7 | CASP3 | not found | Not found | Not found | Not found |
8 | MAPK1 | NM_138957.3 | Mitogen-activated protein kinase 1 (MAPK1), transcript variant 2, mRNA | 0.095103156 | 0.94434009 |
9 | HSP90AA1 | NM_005348.4 | Heat shock protein 90 alpha family class A member 1 (HSP90AA1), transcript variant 2, mRNA | −0.088807883 | 0.94722009 |
10 | MAPK8 | NM_001323330.2 | Mitogen-activated protein kinase 8 (MAPK8), transcript variant 16, mRNA | −0.03700038 | 1 |
