Figure 5 | Scientific Reports

Figure 5

From: Prolonged insulin-induced hypoglycaemia reduces ß-cell activity rather than number in pancreatic islets in non-diabetic rats

Figure 5

Relative islet to pancreas volume, individual (symbols) and means ± SDs. (A) Week 4: CTRL-M, n = 6; HI-M, n = 8; CTRL-F, n = 7; HI-F, n = 8. (B) Week 8: CTRL-M, n = 9; HI-M, n = 4; CTRL-F, n = 10; HI-F, n = 6. (C) Day 2R: CTRL-M, n = 7; HI-M, n = 6; CTRL-F, n = 3; HI-F, n = 6. (D) Week 4R: CTRL-M, n = 10; HI-M, n = 5; CTRL-F, n = 9; HI-F, n = 9. **p < 0.01, ***p < 0.001 versus control group for the same sex, #p < 0.05 versus CTRL-M. Abbreviations: HI, human insulin; Na, not applicable; P, pancreas; R, recovery (infusion-free period).

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