Table 2 Characteristics of study subjects.

From: Characterization of the unique oral microbiome of children with Down syndrome

Clinical characteristics

Down syndrome (n = 40)

Control (n = 40)

P-value

Dental examination

DMFT/dmft index

 Total

0.65 ± 1.74

0.83 ± 1.14

0.054

 Primary

0.08 ± 0.28

0.00 ± 0.00

0.75

 Mixed

0.94 ± 2.26

0.84 ± 1.23

0.56

 Permanent

0.82 ± 1.59

1.42 ± 1.04

0.047

Dental caries prevalence (%)

Total

20.0

42.5

0.003

Primary

8.3

0

0.37

Mixed

23.5

36.8

0.34

Permanent

27.3

83.3

0.007

PLI

Total

2.13 ± 0.84

1.93 ± 0.69

0.19

Primary

1.75 ± 0.92

1.56 ± 0.50

0.62

Mixed

2.18 ± 0.71

2.11 ± 0.72

0.79

Permanent

2.45 ± 0.78

1.92 ± 0.64

0.08

PD (mm)

Total

2.85 ± 0.73

2.63 ± 0.53

0.17

Primary

2.58 ± 0.50

2.33 ± 0.47

0.34

Mixed

2.94 ± 0.54

2.79 ± 0.52

0.51

Permanent

3.00 ± 1.04

2.58 ± 0.47

0.35

GI

Total

1.78 ± 0.52

1.38 ± 0.66

0.002

Primary

1.58 ± 0.64

1.11 ± 0.57

0.11

Mixed

1.88 ± 0.32

1.63 ± 0.58

0.3

Permanent

1.82 ± 0.57

1.17 ± 0.64

0.01

BOP (%)

Total

82.5

47.5

0.001

Primary

66.7

22.2

0.024

Mixed

88.2

68.4

0.31

Permanent

90.9

33.3

0.007

  1. DMFT/dmft index Decayed, Missing, and Filled Teeth/decayed, missing, and filled teeth index, PLI Plaque Index, PD Probing Depth, GI Gingival Index, BOP Bleeding on Probing.
  2. Values in DMFT/dmft index, PLI, PD, GI indicate mean ± SD.
  3. The Chi-squared test (Fisher’s exact probability test for dentition comparisons) was used to compare the prevalence of caries and BOP. The Mann–Whitney U test was used to analyze the DMFT/dmft index, PLI, PD, and GI. Bold type in P-value indicates a significant difference (P < 0.05).
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