Figure 6

Reference memory performance as evaluated on the MWM: consistent deficits in TgF344-AD rats across each age for latency to the platform. (a–c) When evaluating latency to the platform (s) for each age-point across Days 1–5, there was a significant effect of Genotype, whereby Tg rats swam longer to locate the hidden platform than WT rats, indicating spatial reference memory impairment. *p < 0.05, **p < 0.01.