Table 2 The top 10 CpG sites in the conditional logistic regression analyses of CpG sites for melanoma cases (n = 183) versus controls (n = 183).

From: Pre-diagnostic DNA methylation in blood leucocytes in cutaneous melanoma; a nested case–control study within the Norwegian Women and Cancer cohort

CpG ID

Position

Gene

OR

95% CI

p-value

FDR adj. p-value

cg09396032

16q24.1

GSE1

0.000349

(0.00002, 0.0054)

1.672e−06

0.85

cg05900127

6q23.2

TBPL1

42.52

(10.61, 170.45)

8.709e−06

0.85

cg19014186

17q23.2

NACA2

7.03

(3.33, 14.84)

1.661e−05

0.85

cg27080643

16p13.3

SLX4

8.94

(3.87, 20.65)

1.709e−05

0.85

cg24287218

6p21.32

HLA-DPA1

10.38

(4.20, 25.66)

2.066e−05

0.85

cg10964388

12q22

NTN4

16.28

(5.50, 48.20)

2.248e−05

0.85

cg17459743

11q14.1

RSF1

0.13

(0.06, 0.29)

2.268e−05

0.85

cg21150053

5p14.1

CDH9

9.78

(4.02, 23.78)

2.330e−05

0.85

cg03347745

14q23.3

N/A

8.94

(3.79, 21.06)

2.538e−05

0.85

cg02804047

6p21.32

C6orf10

0.12

(0.05, 0.28)

2.709e−05

0.85

  1. Adjusted for lifetime number of sunburns, hair colour, and the 10 first surrogate variables.
  2. OR odds ratio, CI confidence interval, FDR False discovery rate.
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