Table 1 Distributions of baseline characteristics among the 198 asthmatic patients and 453 controls.

From: Genetic variants in miR-145 gene are associated with the risk of asthma in Taiwan

Index

Controls (n = 453)

Cases (n = 198)

p-value*

n

%

n

%

 

Age (years)

25–40

285

63.4%

133

67.2%

 

 > 40

168

36.6%

65

32.8%

0.2972

Gender

Male

190

41.9%

83

41.9%

 

Female

263

58.1%

115

58.1%

0.9956

Smoking status

Never

326

72.0%

139

70.2%

 

Ever

127

28.0%

59

29.8%

0.7161

Pulmonary functions (mean ± SD)

FEV1/FVC (%)

80.8 ± 8.1

62.0 ± 13.0

 < 0.0001

FEV1%

92.9 ± 5.8

69.1 ± 12.9

 < 0.0001

Symptoms severity

1 (mild)

  

60

30.3%

 

2

  

65

32.8%

 

3

  

34

17.2%

 

4 (severe)

  

39

19.7%

 
  1. FEV1 forced expiratory volume in first second, FVC forced vital capacity, FEV1% percent of predicted FEV1.
  2. *Chi-square without Yate’s correction test or Student’s t-test.