Table 3 Distributions of rs4705343 genotypic frequencies between asthmatic patient and control groups.
From: Genetic variants in miR-145 gene are associated with the risk of asthma in Taiwan
Polymorphism | Genotype | Cases | Controls | p-Value | OR (95%CI) | Adjusted OR (95%CI)* |
|---|---|---|---|---|---|---|
rs4705343 | TT | 86 (43.4%) | 213 (47.0%) | 1.00 (Ref) | 1.00 (Ref) | |
CT | 95 (48.0%) | 199 (43.9%) | 0.3956 | 1.18 (0.83–1.68) | 1.21 (0.85–1.59) | |
CC | 17 (8.6%) | 41 (9.1%) | 0.9328 | 1.03 (0.55–1.91) | 1.06 (0.58–1.88) | |
Ptrend | 0.6314 | |||||
PHWE | 0.5715 | |||||
Recessive | TT + CT | 181 (91.4%) | 412 (90.9%) | 1.00 (Ref) | 1.00 (Ref) | |
CC | 17 (8.6%) | 41 (9.1%) | 0.9665 | 0.94 (0.52–1.71) | 0.96 (0.57–1.78) | |
Dominant | TT | 86 (43.4%) | 213 (47.0%) | 1.00 (Ref) | 1.00 (Ref) | |
CC + CT | 112 (56.6%) | 240 (53.0%) | 0.4478 | 1.16 (0.83–1.62) | 1.11 (0.84–1.57) |
