Table 2 Rates of loss or gain of visual acuity at 6 and 12 months after treatment for submacular hemorrhage in neovascular age-related macular degeneration.

From: Comparison of treatment methods for submacular hemorrhage in neovascular age-related macular degeneration: conservative versus active surgical strategy

Visual acuity

Observation

(n = 21)

Anti-VEGF monotherapy

(n = 161)

Intravitreal gas tamponade

(n = 31)

Subretinal surgery

(n = 23)

P value*

Gain of ≥ 3 lines†

After 6 months, No. (%)

7 (33)

58 (36)

7 (23)

15 (65)

0.010

After 12 months, no. (%)

6 (29)

56 (35)

7 (23)

8 (35)

0.672

Loss of ≥ 3 lines

After 6 months, No. (%)

3 (14)

17 (11)

9 (29)

5 (22)

0.068

After 12 months, no. (%)

3 (14)

23 (14)

5 (16)

6 (26)

0.171

  1. VEGF, vascular endothelial growth factor; t-PA, tissue plasminogen activator; LogMAR, logarithm of the minimum angle of resolution.
  2. *Chi-square test.
  3. †3 lines = 0.3 LogMAR = EDTRS 15 letters.
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