Figure 6
From: Localized, time-dependent responses of rat cranial bone to repeated mild traumatic brain injuries
No change in volume, surface area or thickness of the parietal bone at 10 weeks after rmTBI. The parietal bone region-of-interest (ROI) consisting of 150 microCT images (a) was sampled from the mediocaudal left parietal bone, adjacent to the midline and Lambda suture margins (scale bar = 2 mm). Neither single nor repeated mTBI influenced mineralized bone volume (b, p = 0.22), total object volume (c, p = 0.32), or exterior surface area (d, p = 0.52). Mean mineralized bone thickness was also not affected by injury (e, p = 0.80), as demonstrated by representative greyscale microCT images from the ROI z-stack center (f, scale bar = 500 µm). Parietal ROIs from both hemispheres were examined but showed comparable findings; hence only the left ROI is presented. N = 5–10/group; one-way ANOVA.
