Table 4 Inhibition parameters of essential oils and aromatic extracts and SARS-CoV-2 Mpro and PLpro.
From: Evaluation of the anti-SARS-CoV-2 properties of essential oils and aromatic extracts
Natural material | SARS-CoV-2 Mpro IC50 (µg/mL) | SARS-CoV-2 PLpro IC50 (µg/mL) ([µM]) |
|---|---|---|
Essential oils | ||
Petitgrain mandarin EO | > 100 | 22.9 ± 4.6 |
DMA | > 100 | 5.20 ± 1.22 (31.5 ± 7.4) |
Guaiacwood EO | 48.01 ± 4.51 | – |
Blue cypress EO | 48.22 ± 3.02 | – |
Lovage root EO | 70.86 ± 4.65 | – |
Siam wood EO | 76.10 ± 1.23 | – |
Extracts | ||
Benzoin Siam resinoid | 5.24 ± 0.22 | – |
Benzoin Sumatra resinoid | 4.20 ± 0.15 | – |
Galbanum resinoid | 34.52 ± 2.27 | – |
Storax resinoid | 46.31 ± 3.52 | – |
Turmeric oleoresin | 12.01 ± 1.31 | 96.15 ± 2.09 |
Labdanum gum refined | 47.44 ± 1.60 | – |
Nasturtium absolute | 72.79 ± 1.12 | – |
Rocket absolute | 3.41 ± 0.32 | – |
Rocket concrete | 4.79 ± 0.04 | – |
Tasmania lanceolata extract | 49.98 ± 1.99 | – |