Table 2 Results of univariable and multivariable analyses of symptom control and local control.
From: Thirty-year clinical experience in gamma knife radiosurgery for trigeminal schwannomas
Factors | Univariable analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|
p value | OR | 95% CI | p value | OR | 95% CI | |
Symptom control | ||||||
Sex | ||||||
Male | – | – | – | |||
Female | 0.22 | 4.00 | 0.45–35.79 | |||
Age | ||||||
< 50 | – | – | – | – | ||
≥ 50 | 0.05 | 0.11 | 0.01–1.00 | 0.99 | ||
Operation | 0.99 | |||||
Hypertension | 0.99 | |||||
Diabetes mellitus | 0.99 | |||||
Volume | ||||||
< 2.7 cm3 | – | – | – | |||
≥ 2.7 cm3 | 0.44 | 2.00 | 0.35–11.53 | |||
Fraction | ||||||
No | – | – | – | – | ||
Yes | 0.01* | 40.50 | 3.00–546.33 | 0.99 | ||
Tumor type | 0.67 | 0.79 | 0.26–2.41 | |||
Tumor location | 0.15 | 1.71 | 0.83–3.54 | |||
Extracranial extension | 0.67 | 1.62 | 0.17–15.48 | |||
T1 signal intensity | 0.19 | 0.23 | 0.03–2.10 | |||
T2 signal intensity | 0.90 | 0.90 | 0.19–4.33 | |||
Cystic portion | 0.29 | 2.68 | 0.44–16.48 | |||
Transient swelling | ||||||
No | – | – | – | – | – | – |
Yes | 0.01 | 10.18 | 1.66–62.61 | 0.04 | 14.54 | 1.06–200.27 |
Central necrosis | 0.13 | 5.47 | 0.61–49.35 | |||
Local control | ||||||
Controlled | – | – | – | – | – | – |
Failed | 0.08 | 5.36 | 0.83–34.61 | 0.09 | 11.41 | 0.67–194.42 |
Medication | 0.99 | |||||
Local control | ||||||
Sex | 0.90 | 0.92 | 0.23–3.68 | |||
Age | ||||||
< 50 | – | – | – | – | – | – |
≥ 50 | 0.09 | 0.28 | 0.07–1.21 | 0.23 | 0.38 | 0.08–1.81 |
Operation | 0.37 | 2.19 | 0.39–12.21 | |||
Hypertension | 0.51 | 0.48 | 0.06–4.16 | |||
Diabetes mellitus | 0.99 | |||||
Volume | ||||||
< 2.7 cm3 | – | – | – | – | – | – |
≥ 2.7 cm3 | 0.04 | 9.08 | 1.08–76.06 | 0.05 | 8.47 | 0.98–73.17 |
Fraction | 0.99 | |||||
Tumor type | 0.41 | 1.45 | 0.60–3.50 | |||
Tumor location | 0.61 | 0.82 | 0.37–1.80 | |||
Extracranial extension | 0.98 | 0.97 | 0.11–8.70 | |||
T1 signal intensity | 0.71 | 1.32 | 0.30–5.75 | |||
T2 signal intensity | 0.61 | 1.40 | 0.38–5.22 | |||
Cystic portion | 0.99 | |||||
Transient swelling | 0.56 | 0.52 | 0.06–4.59 | |||
Central necrosis | 0.14 | 0.29 | 0.05–1.52 | |||
Symptom control | ||||||
Yes | – | – | – | – | – | – |
No | 0.08 | 5.36 | 0.83–34.61 | 0.24 | 3.42 | 0.44–26.39 |
Medication | 0.80 | 0.75 | 0.08–6.82 | |||