Figure 5 | Scientific Reports

Figure 5

From: Non-destructive, continuous monitoring of biochemical, mechanical, and structural maturation in engineered tissue

Figure 5

Optical assessment was validated by strong correlations with destructive testing methods. Destructive biochemical assays showed strong correlations between (A) collagen content and FLIm CH2 LT and (B) proteoglycan content and FLIm CH3 LT. (C) Destructive mechanical testing showed a strong correlation between FLIm CH3 LT and compressive modulus. (D) Comparison between calculated FLIm-based compressive moduli values and compressive moduli values measured via mechanical testing resulted in a high concordance correlation coefficient.

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