Figure 6

Imaging-based homogeneity index for the biochemical and structural characterization of constructs. (A) Representative en face FLIm LT images showing biochemical variations across the sample surface. (B) Example quantification of FLIm CH3 LT homogeneity from samples in panel A. (C) LAP treatment improved biochemical homogeneity from days 17–28 as compared to TGF. (D) FLIm LT homogeneity at day 28 varied with treatment in both CH2 and CH3. (E) An imaging-based homogeneity index combining structural and biochemical information showed significant improvements with LAP treatment at day 28 as compared to CTL and TGF.