Table 1 Demographic and clinicopathological characteristics of healthy controls and patients with malignant breast neoplasms.
From: The impact of Angiopoietin-2 genetic polymorphisms on susceptibility for malignant breast neoplasms
Variable | Controls N = 539 (%) | Patients N = 464 (%) | p value |
|---|---|---|---|
Age (years) | Mean ± S.D | Mean ± S.D | |
40.43 ± 15.62 | 52.89 ± 11.36 | p < 0.05 | |
Cigarette smoking | |||
No | 527 (97.8) | 463 (99.8) | |
Yes | 12 (2.2) | 1 (0.2) | p < 0.05 |
Alcohol consumption | |||
No | 518 (96.1) | 431 (92.9) | |
Yes | 21 (3.9) | 33 (7.1) | p > 0.05 |
Clinical stage | |||
I + II | 365 (78.7) | ||
III + IV | 99 (21.3) | ||
Tumor size | |||
< T2 | 215 (46.3) | ||
≧T2 | 249 (53.7) | ||
Lymph node status | |||
N0 | 255 (55.0) | ||
N1 + N2 + N3 | 209 (45.0) | ||
Distant metastasis | |||
M0 | 452 (97.4) | ||
M1 | 12 (2.6) | ||
Pathological grade | |||
I | 45 (9.7) | ||
II + III | 419 (90.3) | ||
ER status | |||
Negative | 131 (28.2) | ||
Positive | 333 (71.8) | ||
PR status | |||
Negative | 187 (40.3) | ||
Positive | 277 (59.7) | ||
HER2 status | |||
Negative | 309 (66.6) | ||
Positive | 155 (33.4) | ||
Ki-67 | |||
≤ 14% | 136 (29.3) | ||
> 14% | 328 (70.7) | ||