Table 5 Distribution frequencies of ANGPT2 haplotypes in healthy controls and patients with malignant breast neoplasms.

From: The impact of Angiopoietin-2 genetic polymorphisms on susceptibility for malignant breast neoplasms

Haplotype block

Controls

N = 1078 (%)

Patients

N = 928 (%)

OR

(95% CI)

rs2442598

A/T

rs734701

T/C

rs1823375

C/G

rs11137037

A/C

rs12674822

G/T

A

C

C

A

G

231 (21.4)

189 (20.4)

Reference

T

T

C

A

T

135 (12.5)

153 (16.5)

1.385 (1.025─1.871)*

T

T

G

A

T

105 (9.7)

108 (11.6)

1.257 (0.904─1.749)

A

C

G

C

G

80 (7.4)

93 (10.0)

1.421 (0.996─2.027)

T

T

C

C

T

82 (7.6)

83 (8.9)

1.237 (0.863─1.774)

A

T

C

C

G

52 (4.8)

56 (6.0)

1.316 (0.862─2.010)

Others#

    

393 (36.6)

246 (26.6)

–

  1. The odds ratios (ORs) and their associated 95% confidence intervals (CIs) were estimated by logistic regression models. *p < 0.05 was considered to be statistically significant. # denotes all other 25 haplotypes without significance.
  2. Significant values are in bold.
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