Table 4 Association between elevation of transaminases and abdominal pain pattern in SARS-CoV2 patients, before and after adjustment for sex, age, abdominal surgery during hospital stay (complete case analysis) and association between mortality and/or ICU admission and/or IMCU admission and elevation of transaminases before and after adjustment for sex, age, (complete case analyses).
From: Abdominal pain patterns during COVID-19: an observational study
Elevation of transaminases and abdominal pain pattern | Univariate logistic regression | Multivariate logistic regression | ||||
|---|---|---|---|---|---|---|
OR | 95% CI | p value | OR | 95% CI | p value | |
History of abdominal pain or abdominal point tenderness | ||||||
Baseline AST ≥ 5× upper value | 0.71 | 0.15–3.34 | 0.668 | 0.85 | 0.18–4-03 | 0.841 |
Baseline ALT ≥ 5× upper value | 2.85 | 0.37–21.93 | 0.315 | 1.66 | 0.16–17.25 | 0.669 |
History of right upper region pain | ||||||
Baseline AST ≥ 5× upper value | 3.40 | 0.41–27.81 | 0.255 | 4.10* | 0.48–34.84* | 0.197* |
Baseline ALT ≥ 5× upper value | 11.63 | 1.16–116-78 | 0.037 | 30.94* | 1.77–539.64* | 0.019* |
History of epigastric region pain | ||||||
Baseline AST ≥ 5× upper value | 2.49 | 0.31–20.15 | 0.393 | 3.29 | 0.39–27.77 | 0.275 |
Baseline ALT ≥ 5× upper value | 26.62 | 3.61–196.41 | 0.001 | 19.32 | 2.13–175.17 | 0.008 |
Murphy’s sign | ||||||
Baseline AST ≥ 5× upper value | 16.81 | 3.17–89.09 | 0.001 | 24.54 | 4.18–144.12 | < 0.001 |
Baseline ALT ≥ 5× upper value | 23.30 | 2.23–243.75 | 0.009 | 17.77 | 0.92–343.41 | 0.057 |
Mortality and/or ICU admission and/or IMCU admission and elevation of transaminases | ||||||
Baseline AST ≥ 5× upper value | 17.63 | 2.24–138.50 | 0.006 | 16.03 | 1.95–131.63 | 0.010 |
Baseline ALT ≥ 5× upper value | 0.56 | 0.06–5.41 | 0.616 | 0.64 | 0.05–7.54 | 0.724 |