Figure 3

Induced fit docked representation of acarbose (a) and the superimposed of the synthesized compounds (b). The N-terminal domain and the subdomain of the α-glycosidase are colored in yellow and blue, respectively. Compounds 8p, 8a, 8h, and 8f with lower steric size shown in cyan color while compounds 8d, 8g, 8e, 8c, 8b, 8m, 8k, 8n, 8l, and 8o with higher steric size shown in green color.