Table 2 Characteristics before and after the first renal replacement therapy (RRT) session.

From: Natraemia variations induced by acute dialysis in critically ill patients: a database study

N = 215 patients

N (%) or Median [interquartile range]

Before 1st RRT

After 1st RRT

p value

Clinical characteristics

Weight (kg)

80.0 [69.1–92.6]

85.0 [71.1–97.3]

0.12

Temperature (°C)

36.6 [35.9–37.3]

36.8 [36.2–37.3]

< 0.001

MAP (mmHg)

74 [67–84]

79 [68–87]

0.03

HR (bpm)

92 [73–113]

94 [79–113]

0.11

RR (bpm)

22 [19–27]

22.0 [19–27]

0.74

SpO2 (%)

97 [95–99]

97 [95–99]

0.82

Urine output (mL/kg/h)

0.11 [0.00–0.68]

0.06 [0.00–0.36]

0.08

Mechanical ventilation

132 (61.4)

135 (62.8)

0.05

Catecholamine infusion

124 (57.6)

129 (60.0)

0.03

Biological characteristics

Sodium (mmol/L)

135 [131–139]

140 [137–143]

< 0.001

Glycaemia (mmol/l)

7.8 [6.0–11.7]

6.4 [5.3–8.2]

< 0.001

Blood urea (mmol/L)

19.7 [12.2–31.8]

8.2 [5.1–15.2]

< 0.001

Calculated osmolarity (mmol/L)

274 [266–282]

283 [276–288]

< 0.001

Potassium (mmol/L)

4.8 [4.1–5.6]

4.1 [3.7–4.5]

< 0.001

Bicarbonate (mmol/L)

17.4 [14.5–21.4]

22.5. [19.4–25.4]

< 0.001

Protein (g/L)

58.0 [52.0–64.0]

57.5 [53.0–63.8]

0.86

Albumin (g/L)

24.5 [19.0–29.0]

25.0 [19.0–28.5]

0.93

Haemoglobin (g/dL)

10.0 [8.4–12.2]

9.9 [8.3–11.8]

0.002

Creatinine (μmol/L)

257 [162–513]

141 [93–301]

< 0.001

pH

7.24 [7.16–7.34]

7.36 [7.26–7.43]

< 0.001

Lactate (mmol/L)

2.4 [1.0–7.0]

2.3 [1.2–6.1]

0.02

Dialysate-to-serum Na+ gradient (mmol/L)

12.0 [8.0–16.0]

7.0 [4.5–10.0]

< 0.001

∆Na+ (mmol/L)

5.0 [1.0–7.5]

∆Osmolarity (mmol/L)

8.1 [0.7–13.8]

  1. RRT renal replacement therapy, MAP mean arterial pressure, HR heart rate, RR respiratory rate, ∆: change during RRT (value after RRT − value before RRT).