Table 2 Demographic and clinical information of the studied groups is shown in the top table.
From: The trend of disruption in the functional brain network topology of Alzheimer’s disease
Group | CN | EMCI | LMCI | AD | p | F |
|---|---|---|---|---|---|---|
Demographic and clinical information | ||||||
Number | 23 | 23 | 23 | 23 | - | - |
Male, female | 8,15 | 12,11 | 10,13 | 11,12 | .673 | - |
Age (mean ± SD) | \(75.82 \pm 9.44\) | \(75.29 \pm 6.36\) | \(72.26 \pm 7.05\) | \(77.75 \pm 3.75\) | .396 | 1.00 |
MMSE (mean ± SD) | \(28.96 \pm 1.17\) | \(28.32 \pm 1.89\) | \(25.87 \pm 3.86\) | \(20.32 \pm 4.26\) | < 0.001 | 33.16 |
GDSCALE (mean ± SD) | \(1.04 \pm 1.41\) | \(1.80 \pm 1.85\) | \(1.94 \pm 2.29\) | \(1.37 \pm 1.32\) | .588 | 0.65 |
Global CDR (mean ± SD) | \(0.40 \pm 0.13\) | \(0.39 \pm 0.24\) | \(0.49 \pm 0.25\) | \(0.96 \pm 0.40\) | < 0.001 | 46.41 |
FAQ (mean ± SD) | \(0.25 \pm 1.22\) | \(2.77 \pm 4.22\) | \(5.06 \pm 6.68\) | \(18.26 \pm 7.87\) | < 0.001 | 46.61 |
NPI-Q (mean ± SD) | \(0.67 \pm 1.54\) | \(2.47 \pm 2.52\) | \(2.08 \pm 1.98\) | \(4.85 \pm 3.78\) | .002 | 5.41 |
Pairwise comparison | CN-AD | EMCI-AD | LMCI-AD | CN-EMCI | CN-LMCI | EMCI-LMCI |
|---|---|---|---|---|---|---|
The pairwise t-test comparison | ||||||
Age | 0.932 | 0.539 | 0.202 | 0.878 | 0.512 | 0.919 |
MMSE | < 0.001 | < 0.001 | < 0.001 | 0.880 | 0.047 | 0.233 |
GDSCALE | 0.817 | 0.961 | 0.982 | 0.523 | 0.596 | 0.999 |
Global CDR | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.515 |
FAQ | < 0.001 | < 0.001 | < 0.001 | 0.582 | 0.060 | 0.581 |
NPI-Q | 0.429 | 0.633 | < 0.001 | 0.987 | 0.067 | 0.029 |
