Figure 8

Boxplots of upregulated and downregulated genes differentially expressed between DWC and T1DM with complications. Fig. (A,B) show corresponding boxplots for the upregulated genes (KIAA1614, TRDN) whereas Fig. (C–K) show corresponding boxplots for the downregulated genes (DPPA5, DNM3OS, PPP1R1B, OR2T6, TCEB3C, OR8H1, IFNA4, OR11H12, OR4K15). Significance was calculated using one-way ANOVA between the DWC group versus the complication groups. P < 0.05 was considered significant (*P < 0.05; **P < 0.01, ***P < 0.001, ****P < 0.0001). DWC T1DM without complication, HL Hyperlipidemia, NP Neuropathy, HT Hypothyroidism, KA Ketoacidosis, PCOS Polycystic Ovarian Syndrome.