Figure 5
From: Neuropathologic and molecular aspects of a canine distemper epizootic in red foxes in Germany
Identification of demyelination, axonal damage and apoptotic cells in infected foxes. (a) Lack of CNPase staining (arrow), cerebrum. (b) Lack of Luxol fast blue (LFB) staining, cerebellum. (c) β-APP+ damaged axons within demyelinating lesion, cerebellum. (d) Cleaved caspase-3+ apoptotic cells, cerebrum. (e) Quantification of foci lacking CNPase staining (CNPase-negative foci) within different brain regions. (f) Quantification of foci lacking LFB straining (LFB-negative foci) within different brain regions. (g) Quantification of β-APP+ axons within different brain regions. (h) Quantification of cleaved caspase-3+ apoptotic cells within different brain regions. (e–h) Bars display mean values and standard deviations. Asterisks indicate statistical significance levels, * ≤ 0.05. Scale bars = 100 µm.
