Figure 5 | Scientific Reports

Figure 5

From: Structure–function characterization of an aldo–keto reductase involved in detoxification of the mycotoxin, deoxynivalenol

Figure 5

Model of the ternary complex of DepBRleg. (A) Binding orientation for 3-keto-DON for hydride attack at the re-face. π-stacking interactions between Phe-84 and the cyclohexene ring are shaded yellow. (B) Binding orientation for 3-keto-DON for hydride attack at the si-face. (C) Multiple sequence alignments depicting the sequence variability at positions corresponding to Phe-84 and Ala-123 in DepBRleg with that of various AKR family representatives.

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