Figure 6 | Scientific Reports

Figure 6

From: Activation of recombinational repair in Ewing sarcoma cells carrying EWS-FLI1 fusion gene by chromosome translocation

Figure 6

HR and NHEJ models for chromosome translocation. The HR (A) and NHEJ (B) models to explain t(11;22) chromosome translocation are schematized. In the HR model, one DSB is required in either chromosome, and TL is obtained with a 1/2 chance. On the other hand, in the NHEJ model, two DSBs are necessary in both chromosomes, and the probability of reciprocal TL is 1/3. The results also include dicentric chromosomes and fragments.

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