Table 2 General characteristics of subjects according to CETP genotype in HEXA and KNHANES.
CETP | p value | |||
|---|---|---|---|---|
CC | CT | TT | ||
HEXA | ||||
Subject (n, %) | 20,523(38.3) | 25,225(47.1) | 7,857(14.7) | |
Age (years) | 53.8 ± 8.0 | 53.8 ± 8.0 | 53.9 ± 8.0 | 0.8017 |
Sex (male) | 7,122(34.7) | 8,698(34.5) | 2.662(33.9) | 0.4276 |
Systolic blood pressure (mmHg) | 122.5 ± 14.8 | 122.4 ± 14.8 | 122.5 ± 14.7 | 0.6488 |
Diastolic blood pressure (mmHg) | 75.8 ± 9.7 | 75.8 ± 9.7 | 75.8 ± 9.8 | 0.6183 |
Fasting glucose (mg/dL) | 95.0 ± 19.8 | 94.9 ± 19.7 | 94.9 ± 18.5 | 0.8042 |
Total cholesterol (mg/dL) | 196.1 ± 35.5 | 197.7 ± 35.8 | 200.0 ± 35.9 | < 0.0001 |
HDL-cholesterol (mg/dL) | 52.2 ± 12.6 | 54.3 ± 13.2 | 56.4 ± 13.8 | < 0.0001 |
LDL-cholesterol (mg/dL) | 119.3 ± 32.0 | 119.3 ± 32.3 | 119.6 ± 32.1 | 0.6610 |
Triglycerides (mg/dL) | 126.9 ± 86.5 | 124.2 ± 85.1 | 123.2 ± 84.4 | 0.0004 |
AST (IU/L) | 23.9 ± 33.2 | 23.7 ± 13.8 | 23.6 ± 13.3 | 0.5443 |
ALT (IU/L) | 22.6 ± 29.3 | 22.3 ± 17.2 | 22.3 ± 18.8 | 0.3703 |
Alcohol consumption (Drinker, %) | 9,051(44.1) | 11.218(44.8) | 3,482(44.3) | 0.2054 |
KNHANES | ||||
Subject (n, %) | 5,802(38.9) | 6,949(46.5) | 2,180(14.6) | |
Age (years) | 46.5 ± 16.9 | 46.7 ± 16.8 | 46.4 ± 16.6 | 0.6785 |
Sex (male) | 2,783(48.0) | 3,450(50.0) | 1,048(48.1) | 0.1310 |
Systolic blood pressure (mmHg) | 117.5 ± 16.5 | 117.7 ± 16.3 | 117.6 ± 15.9 | 0.7698 |
Diastolic blood pressure (mmHg) | 75.2 ± 10.6 | 75.3 ± 10.5 | 75.4 ± 10.6 | 0.6617 |
Fasting glucose (mg/dL) | 98.5 ± 22.2 | 98.5 ± 22.0 | 98.8 ± 22.5 | 0.8674 |
Total cholesterol (mg/dL) | 185.8 ± 36.1 | 188.6 ± 36.3 | 191.4 ± 35.9 | < 0.0001 |
HDL-cholesterol (mg/dL) | 49.3 ± 11.9 | 50.9 ± 12.3 | 52.7 ± 12.3 | < 0.0001 |
LDL-cholesterol (mg/dL) | 115.0 ± 33.7 | 119.2 ± 34.1 | 118.5 ± 33.8 | < 0.0001 |
Triglycerides (mg/dL) | 135.2 ± 114.1 | 134.9 ± 107.3 | 137.0 ± 115.8 | 0.7352 |
AST (IU/L) | 22.7 ± 15.8 | 22.3 ± 11.6 | 22.3 ± 10.7 | 0.1381 |
ALT (IU/L) | 22.2 ± 22.9 | 21.6 ± 16.8 | 22.0 ± 17.3 | 0.2100 |
Alcohol consumption (Drinker, %) | 3,842(66.2) | 4,654(67.0) | 1,432(65.7) | 0.4605 |