Table 2 Univariable and multivariable binary logistic regression analysis of the effect of baseline, imaging, and procedural variables on pCore overestimation and good functional outcome (mRS 0–2).

From: Low baseline ischemic water uptake is directly related to overestimation of CT perfusion-derived ischemic core volume

Predictor

Core overestimation

Good outcome (mRS 0–2) at 90 days

Unadjusted RR (95% CI)

Adjusted RR* (95% CI)

Unadjusted RR (95% CI)

Adjusted RR* (95% CI)

Age (years)

1.02 (0.99–1.04)

0.97 (0.96–0.98)

0.97 (0.96–0.98)

Sex

0.79 (0.46–1.35)

1.27 (0.83–1.94)

NIHSS

1.02 (0.99–1.05)

0.93 (0.90–0.96)

0.95 (0.92–0.99)

ASPECTS

1.21 (1.05–1.39)

1.28 (1.09–1.51)

1.2 (1.11–1.37)

1.18 (1.06–1.31)

pCore

1.01 (1.01–1.02)

1.02 (1.01–1.02)

0.99 (0.98–1.00)

NWU (%)

0.93 (0.90–0.97)

0.94 (0.89–0.98)

0.98 (0.95–1.01)

Intravenous alteplase

1.23 (0.76–1.96)

1.55 (0.98–2.45)

Onset to imaging (min)

1.00 (0.99–1.00)§

1.00 (1.00–1.00)§

1.00 (1.00–1.00)

Onset to recanalization (min)

1.00 (0.99–1.00)§

1.00 (0.99–1.00)§

1.00 (1.00–1.00)

Successful reperfusion (eTICI 2c/3)

1.18 (0.69–2.01)

1.61 (1.05–2.46)

1.55 (1.06–2.28)

  1. mRS modified Rankin Scale; RR relative risk; NIHSS National Institutes of Health Stroke Scale; ASPECTS Alberta Stroke Program Early CT Score; NWU net water uptake; eTICI expanded Thrombolysis in Cerebral Infarction.
  2. *Significant predictors in univariable regression were used to build the multivariable model.
  3. §Values are rounded to the nearest decimal.
  4. Significant associations are shown in bold.