Table 2 Acquired antibiotic resistance genes detected in E. coli isolates recovered from patients attending the National Hospital Abuja, Nigeria expressed in frequencies.

From: Molecular characterization of multi drug resistant Escherichia coli isolates at a tertiary hospital in Abuja, Nigeria

Antibiotic classa

Resistance determinants of E. coli isolates (no of isolates)b

Aminoglycoside

aac(3)-IId (25), aac(3)-IIe (31), aac(6′)-Ib-cr (47), aadA5 (57), ant(2′′)-Ia (2), aph(3′′)-Ib (60), aph(3′′)-VI (1), aph(6)-Id (61)

β-Lactam

blaCTX-M-14 (3), blaCTX-M-15 (71), blaCTX-M-27 (3), blaCTX-M-55 (1), blaCTX-M-65 (1), blaCTX-M-130 (1), blaCTX-M-176 (1), blaOXA-1 (50), blaOXA-2 (4), blaTEM-1(53), blaTEM-190(1), blaCMY-2 (7)

Carbapenem

blaNDM-1 (2), blaNDM-5 (4)

Erythromycin

ermB (11) ermD (2)

Fosfomycin

fosA3 (1) fosA7 (1)

Macrolide

mdfA (101), mphA (69)

Phenicol

catA1 (23), catA2 (3), catB3 (48), cmlA1 (4)

Sulfonamide

sul1 (67), sul2 (52), sul3 (5)

Tetracycline

tetA (53), tetB (78), tetM (1)

Trimethoprim

dfrA1 (3), dfrA7 (2), dfrA8 (1), dfrA12 (11), dfrA14 (10), dfrA17 (53), dfrA82 (2), dfrB4 (1)

Quinolone

qepA (3), qepA1 (3), qepA2 (1), qepA4 (5), qnrB19 (1), qnrS1 (8), qacE (1)

Multi drug class gene—phenicols, lincosamids

mdtM (94), emrD (2)

  1. aDrugs corresponding to each antibiotic class used in our study are as follows: aminoglycosides, streptomycin, gentamicin; beta-lactams, ampicillin, ceftriaxone, cefotaxime, ceftazidime, ceftiofur, cefoxitin, amoxicillin-clavulanic acid; phenicols, chloramphenicol; folate pathway antagonists, trimethoprim-sulfamethoxazole, sulfisoxazole; tetracycline.
  2. bThe numbers of isolates carrying each resistance determinant are presented in parentheses.
Back to article page