Figure 5

(A) Representative coronal PET image 50–60 min p.i. from a HT-29 tumor bearing mouse injected with [18F]21 (left) and, on the following day, with [18F]21 together with 3 (100 nmol, right). Red arrows indicate the tumor. B, C: Time activity curves of [18F]21 in HT-29 tumors (B) and kidneys (C) in HT-29 tumor-bearing mice as determined by PET. Each point represents the mean ± standard deviation in %ID/g from animals injected with [18F]21 (n = 8) and from animals coinjected with [18F]21 and 3 (100 nmol/animal, n = 4).