Table 4 Comparion clinical and lesion characteristics in vessels with DS ≤ 50% between the anatomical–functional reverse mismatch and non-reverse mismatch groups.
From: Impact of overestimation of fractional flow reserve by adenosine on anatomical–functional mismatch
Reverse mismatch Pd/PaADN ≤ 0.80 (n = 76) | Non-mismatch Pd/PaADN > 0.80 (n = 79) | p value | |
|---|---|---|---|
Age, yrs | 71 (63–78) | 72 (67–78) | 0.436 |
Male, n (%) | 62 (82%) | 53 (67%) | 0.039 |
Body mass index, kg/m2 | 24.6 (22.0–27.0) | 23.4 (21.2–25.5) | 0.055 |
Hypertension, n (%) | 59 (78%) | 61 (77%) | 0.235 |
Diabetes mellitus, n (%) | 32 (42%) | 30 (38%) | 0.600 |
Dyslipidemia, n (%) | 46 (61%) | 55 (70%) | 0.779 |
Target vessel (LAD), n (%) | 55 (72%) | 43 (54%) | 0.021 |
Proximal lesion*, n (%) | 34 (45%) | 30 (38%) | 0.393 |
Multivessel disease, n (%) | 44 (58%) | 41 (52%) | 0.453 |
Quantitative coronary angiography | |||
Reference diameter, mm | 2.6 (2.3–3.1) | 2.9 (2.6–3.3) | 0.002 |
Minimal luminal diameter, mm | 1.5 (1.3–1.8) | 1.7 (1.6–2.1) | < 0.001 |
DS, % | 42.5 (38.7–46.6) | 41.5 (35.1–45.6) | 0.058 |
Lesion length, mm | 11.1 (7.6–17.0) | 9.6 (7.2–15.0) | 0.321 |
Hemodynamic parameters | |||
Heart rate at baseline, beats/min | 65 (57–71) | 67 (61–74) | 0.102 |
Pa at baseline, mmHg | 90 (79–98) | 94 (83–100) | 0.128 |
Pd/Pa ratio at baseline | 0.91 (0.87–0.93) | 0.95 (0.93–0.99) | < 0.001 |
Pd/PaADN | 0.75 (0.69–0.78) | 0.87 (0.84–0.91) | N.A |
Pd/PaPAP | 0.73 (0.66–0.76) | 0.86 (0.82–0.89) | N.A |
Pd/PaADN – Pd/PaPAP | 0.03 (0.01–0.03) | 0.01 (0–0.04) | 0.224 |
