Figure 3

Pathway analysis of markers metabolites of testosterone levels identified by sPLS-DA analysis. Metabolic Set Enrichment Analysis (MSEA) results based on search in The Small Molecule Pathway Database (SMPDB) library. Bar graphs illustrating the enrichment overview of the top metabolic pathways of metabolites present in clusters 2, 3, and 4 with recovery or tendency to recover the respective abundance profiles. Color intensity (yellow to red) indicates their increasing statistical significance.