Table 3 Comparison of clinicopathological metrics between the AFP positive and negative groups in 2124 small HCC patients matched by propensity scores.
Variable | AFP (−) (n = 1062) | AFP (+) (n = 1062) | P value |
|---|---|---|---|
Age, (mean ± SD), year | 64.3 ± 10.3 | 63.9 ± 9.5 | 0.265 |
Gender, n (%) | |||
Male | 1239 (77.3) | 1216 (75.9) | 0.337 |
Female | 363 (22.7) | 386 (24.1) | |
Race, n (%) | |||
Black | 142 (8.9) | 195 (12.2) | 0.002 |
White | 1143 (71.3) | 1063 (66.4) | |
Others* | 317 (19.8) | 344 (21.5) | |
Marital status, n (%) | |||
Married | 986 (61.5) | 961 (60.0) | 0.366 |
Unmarried | 616 (38.5) | 641 (40.0) | |
Tumor size, mean ± SD, (mm) | 30.0 ± 11.2 | 29.6 ± 11.0 | 0.881 |
Histological grade, n (%) | |||
I | 675 (42.1) | 642 (40.1) | 0.495 |
II | 778 (48.6) | 805 (50.2) | |
III + IV | 149 (9.3) | 155 (9.7) | |
T stage, n (%) | |||
T1 | 1095 (68.4) | 1066 (66.5) | 0.274 |
T2 | 507 (31.6) | 536 (33.5) | |
N stage, n (%) | |||
N0 | 1579 (98.6) | 1579 (98.6) | 1.000 |
N1 | 23 (1.4) | 23 (1.4) | |
Fibrosis score, n (%) | |||
F0 (0–4) | 171 (10.7) | 136 (8.5) | 0.021 |
F1 (5–6) | 502 (31.3) | 562 (35.1) | |
Unknown | 929 (58.0) | 904 (56.4) | |
Metastatic status, n (%) | |||
Negative | 1570 (98.0) | 1556 (97.1) | 0.109 |
Positive | 32 (2.0) | 46 (2.9) | |