Table 3 Comparison of clinicopathological metrics between the AFP positive and negative groups in 2124 small HCC patients matched by propensity scores.

From: Association of alpha-fetoprotein and metastasis for small hepatocellular carcinoma: A propensity-matched analysis

Variable

AFP (−) (n = 1062)

AFP (+) (n = 1062)

P value

Age, (mean ± SD), year

64.3 ± 10.3

63.9 ± 9.5

0.265

Gender, n (%)

Male

1239 (77.3)

1216 (75.9)

0.337

Female

363 (22.7)

386 (24.1)

 

Race, n (%)

Black

142 (8.9)

195 (12.2)

0.002

White

1143 (71.3)

1063 (66.4)

 

Others*

317 (19.8)

344 (21.5)

 

Marital status, n (%)

Married

986 (61.5)

961 (60.0)

0.366

Unmarried

616 (38.5)

641 (40.0)

 

Tumor size, mean ± SD, (mm)

30.0 ± 11.2

29.6 ± 11.0

0.881

Histological grade, n (%)

I

675 (42.1)

642 (40.1)

0.495

II

778 (48.6)

805 (50.2)

 

III + IV

149 (9.3)

155 (9.7)

 

T stage, n (%)

T1

1095 (68.4)

1066 (66.5)

0.274

T2

507 (31.6)

536 (33.5)

 

N stage, n (%)

N0

1579 (98.6)

1579 (98.6)

1.000

N1

23 (1.4)

23 (1.4)

 

Fibrosis score, n (%)

F0 (0–4)

171 (10.7)

136 (8.5)

0.021

F1 (5–6)

502 (31.3)

562 (35.1)

 

Unknown

929 (58.0)

904 (56.4)

 

Metastatic status, n (%)

Negative

1570 (98.0)

1556 (97.1)

0.109

Positive

32 (2.0)

46 (2.9)

 
  1. Significant values are in bold.
  2. *The others comprise American Indian/Alaska Native, Asian/Pacific Islander. AFP alpha-fetoprotein, HCC hepatocellular carcinoma.