Table 6 Effect of immunosuppressants on P-gp expression in UC.

From: Comparison of effects of aminosalicylic acid, glucocorticoids and immunosuppressive agents on the expression of multidrug-resistant genes in ulcerative colitis

Group

Total (n)

Positive (n)

Negative (n)

Positive rate (%)

Control group

45

14

31

31.1

Effective group

pre-treatment

28

5

23

23.9a

Post-treatment

28

6

22

19.8ab

Ineffective group

Pre-treatment

9

3

6

33.3d

Post-treaent

9

4

5

44.4ace

  1. aP < 0.05 versus normal control.
  2. bP > 0.05 versus pre-treatment.
  3. cP < 0.05 versus pre-treatment.
  4. dP < 0.05 versus effective group pre-treatment.
  5. eP < 0.05 versus effective group post-treatment.