Table 8 Effect of glucocorticoid on the expression level of MDR1 gene in UC (mean ± SD).

From: Comparison of effects of aminosalicylic acid, glucocorticoids and immunosuppressive agents on the expression of multidrug-resistant genes in ulcerative colitis

Group

Total (n)

Relative expression of MDR1

Control group

45

1.374 ± 0.022

Effective group

Pre-treatment

42

0.675 ± 0.103a

Post-treatment

42

0.509 ± 0.106ab

Ineffective group

Pre-treatment

11

1.249 ± 0.073d

Post-treatment

11

1.867 ± 0.151ace

  1. aP < 0.05 versus control group.
  2. bP > 0.05 versus pre-treatment.
  3. cP < 0.05 versus pre-treatment.
  4. dP < 0.05 versus effective group pre-treatment.
  5. eP < 0.05 versus effective group post-treatment.
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