Table 1 Homology between the ORF of the putative KP enzymes of L. stagnalis with orthologues from different organisms.
From: Identification and characterization of the kynurenine pathway in the pond snail Lymnaea stagnalis
Enzyme | Lymnaea stagnalis | Homo sapiens | Mus musculus | Rattus norvegicus | Aplysia californica | Biomphalaria glabrata | Pomacea canaliculata | Caenorhabditis elegans | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Contig | Transcript | Predicted size ORF (aa) | Ortholog | Identities | E-value BLASTp | Ortholog | Identities | E-value BLASTp | Ortholog | Identities | E-value BLASTp | Ortholog | Identities | E-value BLASTp | Ortholog | Identities | E-value BLASTp | Ortholog | Identities | E-value BLASTp | Ortholog | Identities | E-value BLASTp | |
Lym IDO-like | FCFB01037212.1 FCFB01037213.1 FCFB01037214.1 | FX190660.1 | 443 | NP_002155.1 | 152/412 (37%) | 1.0E-84 | NP_032350.1 | 147/407 (36%) | 1.0E-84 | NP_076463.1 | 154/408 (38%) | 8.0E-90 | XP_005113130.1 | 74/211 (35%) | 1.0E-31 | XP_013068348.1 | 262/443 (59%) | 0.0E + 00 | XP_025080939.1 | 191/404 (47%) | 5E-140 | – | – | – |
Lym TDO-like | FCFB01109750.1 FCFB01109751.1 FCFB01255639.1 FCFB01297038.1 | FX224560.1 FX206683.1 FX225637.1 | 418 | NP_005642.1 | 198/380 (52%) | 4.0E-133 | NP_064295.2 | 185/354 (52%) | 4.0E-127 | NP_071798.1 | 189/355 (53%) | 5.0E-130 | XP_012941285.1 | 117/170 (69%) | 7.0E-74 | XP_013068951.1 | 339/419 (81%) | 0.0E + 00 | XP_025088197.1 | 264/398 (66%) | 0.0E + 00 | NP_498284.1 | 200/370 (54%) | 9.0E-135 |
Lym AFMID-like | FCFB01077058.1 FCFB01161380.1 FCFB01232167.1 | FX191423.1 | 272 | NP_001010982.2 | 95/242 (39%) | 6.0E-53 | NP_082103.1 | 98/270 (36%) | 1.0E-49 | NP_001104836.1 | 99/274 (36%) | 2.0E-48 | XP_005112504.2 | 178/275 (65%) | 6.0E-138 | XP_013073423 | 115/155 (74%) | 1.0E-80 | XP_025114029.1 | 160/277 (58%) | 2.0E-119 | – | – | – |
Lym KMO-like | FCFB01020652.1 | FX185910.1 | 479 | NP_003670.2 | 238/437 (54%) | 0.0E + 00 | NP_598570.1 | 249/440 (57%) | 0.0E + 00 | NP_067604.1 | 235/417 (56%) | 5.0E-175 | XP_012945866.1 | 324/464 (70%) | 0.0E + 00 | XP_013064773.1 | 59/138 (43%) | 2.0E-35 | XP_025105148.1 | 280/437 (64%) | 0.0E + 00 | NP_506025.1 | 225/460 (49%) | 2.0E-156 |
Lym AADAT-like | FCFB01016053.1 | FX183988.1 | 450 | NP_001273611.1 | 84/329 (26%) | 9.0E-28 | NP_035964.1 | 98/405 (24%) | 3.0E-19 | NP_058889.1 | 88/334 (26%) | 1.0E-22 | XP_012941811.1 | 78/334 (23%) | 4.0E-14 | XP_013087071.1 | 138/279 (49%) | 1.0E-87 | – | – | – | – | – | – |
Lym KYAT-like | FCFB01033100.1 | FX191915.1 | 462 | NP_001008661.1 | 234/442 (53%) | 1.0E-175 | NP_001280489.1 | 236/436 (54%) | 2.0E-168 | NP_001015037.1 | 231/444 (52%) | 2.0E-167 | XP_012935490.1 | 323/425 (76%) | 0.0E + 00 | XP_013067258.1 | 144/184 (78%) | 8.0E-109 | XP_025114352.1 | 280/451 (62%) | 0.0E + 00 | NP_001024823.1 | 187/412 (45%) | 2.0E-133 |
Lym KYNU-like | FCFB01070793.1 | FX188572.1 | 485 | NP_001186170.1 | 247/461 (54%) | 5.0E-177 | NP_081828.1 | 243/463 (52%) | 4E-172 | NP_446354.1 | 247/455 (54%) | 4.0E-171 | XP_005108249.1 | 379/470 (81%) | 0.0E + 00 | XP_013068429.1 | 107/132 (81%) | 9.0E-76 | XP_025090853.1 | 311/482 (65%) | 0.0E + 00 | NP_509023.1 | 243/454 (54%) | 7.0E-175 |
Lym ACMSD-like | FCFB01196791.1 FCFB01209656.1 FCFB01252153.1 FCFB01272611.1 FCFB01319919.1 | FX187039.1 | 355 | NP_612199.2 | 232/331 (70%) | 0.0E + 00 | NP_001028213.1 | 236/336 (70%) | 0.0E + 00 | NP_599199.1 | 235/336 (70%) | 0.0E + 00 | XP_005102237.1 | 282/333 (85%) | 0.0E + 00 | XP_013081878.1 | 301/352 (86%) | 0.0E + 00 | XP_025094288.1 | 249/349 (71%) | 0.0E + 00 | NP_001022935.1 | 167/383 (44%) | 2.0E-106 |
Lym HAAO-like | FCFB01141163.1 | FX195327.1 | 293 | NP_036337.2 | 143/283 (51%) | 3.0E-111 | NP_079601.1 | 143/284 (50%) | 2.0E-100 | NP_064461.1 | 143/284 (50%) | 3.0E-102 | XP_005102960.1 | 210/289 (73%) | 5.0E-170 | XP_013070925.1 | 167/221 (76%) | 4.0E-130 | XP_025104598.1 | 201/291 (69%) | 1.0E-157 | NP_505450.1 | 111/270 (41%) | 3.0E-62 |
