Table 2 Description of analysis population.

Age^‡ (years)

59.6 ± 7.8

59.7 ± 7.8

59.6 ± 7.8

Genetic Risk Score_NT-proBNP^‡

2.5 ± 1.0

2.5 ± 1.0

2.6 ± 1.0

NT-proBNP^† (pg/ml_

70.0 (39.0–132.0)

54.0 (31.0–109.0)

86.0 (52.0–147.0)

monthly Income^† (€)

(n_miss = 284)

1449 (1108–1875)

1520 (1108–2073)

1313 (0937–1875)

Education groups (n_miss = 13)

≤ 10 years

517 (11.5%)

111 (4.9%)

406 (18.0%)

11–13 years

2494 (55.3%)

1073 (47.6%)

1421 (63.0%)

≥ 14 years

1496 (33.2%)

1069 (47.5%)

427 (19.0%)

C-reactive protein^† (mg/l) (n_miss = 11)

0.2 (0.1–0.3)

0.2 (0.2–0.3)

0.2 (0.1–0.3)

Serum Glucose^† (mg/dl) (n_miss = 4)

105.0 (98.0–115.0)

108.0 (101.0–119.0)

103.0 (96.0–111.0)

Total Cholesterol^‡ (mg/dl) (nmiss = 1)

229.1 ± 39.2

225.0 ± 39.1

233.3 ± 39.4

High density lipoprotein cholesterol^‡ (mg/dl) (n_miss = 2)

58.1 ± 17.2

51.1 ± 17.2

65.17 ± 17

Low density lipoprotein cholesterol^‡

(mg/dL) (n_miss = 14)

145.6 ± 36.1

145.5 ± 36.1

145.7 ± 36.8

Triglycerides^† (mg/dL)

(n_miss = 4)

124.0 (90.0–178.0)

137.5(96.0–200.0)

114.0(85.0–159.0)

HBA_1c^† (%) (n_miss = 34)

5.4 (5.1–5.7)

5.4 (5.1–5.8)

5.3 (5–5.7)

Body mass index^‡ (kg/m²) (n_miss = 26)

27.9 ± 4.6

28.2 ± 4.6

27.6 ± 5.2

No physical activity (n_miss = 1)

2072 (45.8%)

1052 (46.5%)

1237 (54.8%)

Smoking (n_miss = 7)

2626 (58.2%)

1622 (71.8%)

1004 (44.5%)

Systolic blood pressure^‡ (mmHg) (n_miss = 12)

133.2 ± 20.8

138.1 ± 20.8

128.2 ± 21.0

Diastolic blood pressure^‡ (mmHg) (n_miss = 11)

81.5 ± 10.8

84.0 ± 10.8

78.9 ± 10.6

Diabetes mellitus

607 (13.4%)

390 (17.2%)

217 (9.6%)

Coronary artery calcification (n_miss = 191)

18.6 (0.0–166.6)

77.1 (6.7–360.5)

1.80 (0.0–43.38)

Stroke at baseline (n_miss = 13)

124 (2.8%)

76 (3.4%)

48 (2.1%)

coronary artery disease at baseline (n_miss = 10)

305 (6.8%)

242 (10.7%)

63 (2.8%)

GFR‡ [ml/min] (n_miss = 5)

79.5 ± 18.4

83.0 ± 18.4

76.0 ± 18.5