Table 4 Exp(βinteraction) and 95% confidence intervals (95% CI) of the interaction term for the interaction of socioeconomic and cardiovascular risk factors by the NT-proBNP-related genetic risk allele sum score on NT-proBNP in linear regression models separately for each socioeconomic and cardiovascular risk factor, adjusted for sex and age (lowest income/education group as reference).
Variable | n | Exp (βinteraction) | 95% confidence interval | p-value |
|---|---|---|---|---|
Income quartiles | 4236 | |||
2. quartile | 1.04 | 0.96–1.13 | 0.29 | |
3. quartile | 1.10 | 1.01–1.19 | 0.03 | |
4. quartile | 1.06 | 0.98–1.15 | 0.17 | |
Education groups | 4507 | |||
11–13 years | 1.02 | 0.94–1.10 | 0.70 | |
≥ 14 years | 1.03 | 0.95–1.13 | 0.45 | |
C-reactive protein (mg/dl) | 4509 | 1.03 | 1.01–1.06 | 0.02 |
Serum glucose† (mg/dl) | 4516 | 1.00 | 0.99–1.02 | 0.82 |
Total cholesterol‡ (mg/dl) | 4519 | 0.99 | 0.96–1.01 | 0.26 |
High density lipoprotein cholesterol‡ (mg/dl) | 4518 | 1.00 | 0.97–1.02 | 0.84 |
Low density lipoprotein cholesterol‡ (mg/dl) | 4506 | 1.00 | 0.97–1.02 | 0.82 |
Triglycerides† (mg/dl) | 4516 | 0.99 | 0.96–1.01 | 0.21 |
HBA1C† (%) | 4486 | 0.99 | 0.96–1.02 | 0.70 |
Body Mass Index‡ (kg/m2) | 4494 | 0.99 | 0.96–1.01 | 0.24 |
Systolic blood pressure‡ (mmHg) | 4508 | 0.99 | 0.96–1.01 | 0.36 |
Diastolic blood pressure‡ (mmHg) | 4509 | 1.00 | 0.97–1.02 | 0.80 |
No physical activity | 4519 | 1.00 | 0.95–1.05 | 0.95 |
Diabetes mellitus | 4520 | 0.96 | 0.89–1.04 | 0.32 |
Smoking | 4513 | 0.98 | 0.93–1.04 | 0.53 |
Coronary artery calcification† | 4329 | 0.99 | 0.99–1.00 | 0.07 |
