Figure 6
From: Cocaine regulation of Nr4a1 chromatin bivalency and mRNA in male and female mice
Pearson’s Correlation Matrices reveal distinct transcriptomic and epigenetic relationships following cocaine exposure in both sexes. (A) Pearson’s Correlation matrix evaluating transcriptomic and epigenetic relationships of Nr4a1 and Cartpt in the striatum of saline- and cocaine-injected males and (B) females. (C) Pearson’s Correlation matrix evaluating transcriptomic and epigenetic relationships of Nr4a1 and Cartpt in the hippocampus of saline- and cocaine-injected males and (D) females. (E) Pearson’s Correlation matrix evaluating transcriptomic and epigenetic relationships of Nr4a1 and Cartpt in the prefrontal cortex of saline- and cocaine-injected males and (F) females. For all Pearson’s Correlation matrices, red indicates a significant positive correlation (p ≤ 0.05) and blue indicates a significant negative correlation (p ≤ 0.05). A gray box indicates a correlation was not analyzed as it violates the rule of independence for Pearson’s Correlation.
