Figure 5
Metascape membership analysis for differentially abundant mRNAs in uEVs of the 6 clusters of similar expression profiles. Gene lists of the 6 SOTA clusters were uploaded to Metascape and membership analysis was performed for selected keywords. The outer ring of each pie (grey) represents the number and percentage of genes in the background that are associated with the membership term. The inner ring of each pie shows the number and percentage of genes in the individual input gene list that are associated with the membership term. The P-value (P) at the top of each pie indicates whether the membership term is significantly enriched. SOTA clusters illustrated in Fig. 4 are shown again at the bottom right. Images created with Metascape webtool (https://metascape.org)32 and modified with Adobe Photoshop v.22.4.3.
