Figure 5

ECM, MRI and gross images of the development of the stomach and intestine in the pig at D20 to 2 days of age. (A) shows the early developing stomach and (B) shows the relationship of the colon to the yolk sac at D20, and at D26, bowel has herniated to the base of the umbilical cord with part of the bowel located outside the abdominal cavity (C) and the bowel is in the process of rotating (D). At D30 (E), a portion of the bowel is still herniated through the normal opening in the fetal abdominal wall and the * shows the posterior limit of the abdominal wall opening and the mesentery is well-formed. At D42, the bowel is completely located within the abdomen, the abdominal wall is intact, and the rotation of the bowel appears completed (F) and by MRI, the spiral colon is well-formed (G). Illustration (H) is an ex-situ specimen of the small bowel and spiral colon in a 2-day old pig. Stm-Stomach, MES-Mesonephros, YS-Yolk sac, Co-Colon, UC-umbilical cord, SB-Small bowel, LB-Large bowel, Mest-Mesentery, Ao-Aorta, SC-Spiral colon, *- Border of the fetal abdominal wall.