Table 1 Comparison between TMX sensitive and TMX resistant groups regarding the different studied parameters.

From: Metabolic/hypoxial axis predicts tamoxifen resistance in breast cancer

 

TMX-sensitive group

TMX-resistant group

Test value

P value

N = 50

N = 50

TUG-1

Median (IQR)

39.75 (32.86–45.99)

210.62 (172.64–220.57)

7.127

 < 0.001**

Range

23.03–136.35

36.60–448.22

miRNA 186-5p

Median (IQR)

168.78 (138.51–180.81)

376.08 (339.77–428.06)

5.933

 < 0.001**

Range

111.73–568.78

111.07–620.37

SIRT3

Median (IQR)

3.57 (2.55–4.54)

2.85 (2.14–3.47)

− 2.642

0.008**

Range

0.46–9.78

0.38–5.69

PPAR alpha

Median (IQR)

1.21 (0.75–2.77)

0.83 (0.64–1.05)

− 2.902

0.004**

Range

0.29–4.56

0.35–2.92

HIF-1

Median (IQR)

1.99 (1.73–2.95)

1.23 (0.99–1.57)

− 5.108

0.001**

Range

0.45–5.72

0.53–3.97

  1. P value > 0.05: non significant; P value < 0.05: significant*; P value < 0.01: highly significant**.
  2. ≠Mann–Whitney test.
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