Table 3 Ocular manifestations among patients with and without graft-versus-host disease.

From: A plethora of ocular surface manifestations in a multidisciplinary ocular graft-versus-host disease unit

 

Without cGVHD n = 22 (%)

With Chronic GVHD n = 60 (%)

p-value†

Conjunctival scarring

0 (0.00)

8 (13.33)

0.007

Meibomian gland dysfunction

16 (72.72)

55 (91,66)

0.001

Corneal opacity

0 (0.00)

4 (6.66)

0.014

Filamentous keratitis

0 (0.00)

6 (10.00)

0.001

Corneal neurotrophic ulcer

0 (0.00)

1 (1.66)

0.497

Infectious keratitis

0 (0.00)

1 (1.66)

0.541

Mucoid secretion

0 (0.00)

15 (25.00)

 < 0.001

Corneal neovascularization

0 (0.00)

6 (10.00)

0.001

Corneal perforation

0 (0.00)

2 (3.33)

0.246

Cataract

4 (18.18)

17 (28.33)

0.018

Retinopathy

2 (9.09)

4 (6.66)

0.795

Ocular surgery

2 (9.09)

17 (28.33)

0.009

  1. Data expressed as frequency of cases in the study sample. †Chi-square test; GVHD: Graft-versus-host disease.
  2. Significant values are in [bold].
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