Figure 2 | Scientific Reports

Figure 2

From: BCGΔBCG1419c increased memory CD8+ T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosis

Figure 2

Long-term protective efficacy against replication of Mtb strain M2 with BCG and BCGΔBCG1419c vaccination. (a, b) CFUs in the lungs and spleens of each subset of mice (n = 6/group) at 10 weeks post-infection were assessed by enumerating viable bacteria. Fold change was presented by comparing the mean CFU values between group. One-way ANOVA with post hoc Tukey’s multiple comparison test was used to evaluate the significance. **p < 0.01 and ***p < 0. 001. The experimental results of one representative experiment are presented.

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