Figure 6 | Scientific Reports

Figure 6

From: HSV-1 0∆NLS vaccine elicits a robust B lymphocyte response and preserves vision without HSV-1 glycoprotein M or thymidine kinase recognition

Figure 6

HSV-1 gM and TK are recognized by antiserum from GFP105- but not 0∆NLS-vaccinated mice. Serum (n = 4 samples/group) from GFP105- and 0∆NLS-vaccinated mice was used to immunoprecipitate virus-encoded proteins from HSV-1-infected Vero cell lysates. Precipitated proteins were analyzed by mass spectrometry. HSV-1 proteins were identified via cross-referencing derivative peptide ions with a reference sequence data base. The bars represent the mean matched peptide abundance/intensity per protein ± SEM, *p < .05 comparing the two groups as determined by multiple t-test using the Holm-Sidak method.

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