Table 3 25 tumor suppressors associated with antler development.
From: Comprehensive transcriptome analysis of sika deer antler using PacBio and Illumina sequencing
Gene symbol | Gene name | FPKM | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
T25 | T45 | T65 | T100 | T130 | Osteosarcoma | Osteosarcoma | Roe deer Antler | Sika deer Antler | ||
PIWIL2 | Piwi-like protein 2 | 7.73 | 7.75 | 7.90 | 4.25 | 3.82 | 0.34 | 1.12 | 7.56 | 6.59 |
PTPRK | Receptor-type tyrosine-protein phosphatase kappa | 3.86 | 3.99 | 3.83 | 12.43 | 11.53 | 0.18 | 0.09 | 8.15 | 6.76 |
BTG3 | Protein BTG3 | 56.87 | 57.58 | 52.51 | 41.24 | 37.12 | 0 | 0 | 14.50 | 20.80 |
TGM3 | Protein-glutamine gamma-glutamyltransferase E | 4.50 | 4.63 | 10.38 | 120.73 | 88.59 | 2.03 | 0 | 14.39 | 16.21 |
FOXO6 | Forkhead box protein O6 | 1.11 | 1.48 | 2.53 | 14.28 | 8.96 | 0.37 | 0.1 | 5.10 | 4.19 |
PTPRC | Receptor-type tyrosine-protein phosphatase C | 1.80 | 2.07 | 1.73 | 4.03 | 6.65 | 0 | 0.15 | 7.92 | 6.90 |
EPHA1 | Ephrin type-A receptor 1 | 2.40 | 2.96 | 6.36 | 68.56 | 58.24 | 3.2 | 0.03 | 15.40 | 11.38 |
IRX1 | Iroquois-class homeodomain protein IRX-1 | 2.87 | 2.26 | 2.35 | 26.45 | 17.65 | 0.44 | 0.18 | 13.41 | 8.64 |
PLCD1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | 88.64 | 132.62 | 98.37 | 39.61 | 50.39 | 9.22 | 11.59 | 64.56 | 67.16 |
GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma | 25.56 | 32.83 | 50.03 | 109.59 | 95.64 | 6.95 | 1.5 | 23.59 | 32.18 |
CEBPA | CCAAT/enhancer-binding protein alpha | 21.14 | 20.48 | 33.60 | 280.77 | 170.46 | 5.25 | 2.09 | 38.33 | 43.15 |
GLI1 | Zinc finger protein GLI1 | 10.31 | 9.10 | 17.96 | 6.60 | 1.51 | 1.09 | 0.25 | 3.12 | 3.15 |
CHST10 | Carbohydrate sulfotransferase 10 | 96.70 | 121.45 | 76.59 | 31.56 | 59.25 | 3.87 | 4.71 | 24.00 | 32.99 |
FAS | Tumor necrosis factor receptor superfamily member 6 | 2.48 | 3.05 | 3.04 | 6.73 | 11.85 | 8.16 | 12.28 | 1.23 | 0.76 |
POU2F3 | POU domain, class 2, transcription factor 3 | 2.14 | 3.66 | 3.97 | 66.32 | 45.87 | 0.82 | 0.01 | 3.08 | 3.10 |
PGRMC2 | Membrane-associated progesterone receptor component 2 | 117.91 | 116.99 | 109.99 | 347.47 | 304.30 | 16.53 | 10.72 | 103.30 | 118.08 |
GUCY2C | Heat-stable enterotoxin receptor | 0.31 | 0.28 | 0.26 | 1.89 | 1.28 | 0.22 | 0.09 | 1.15 | 0.80 |
TFPI2 | Tissue factor pathway inhibitor 2 | 43.01 | 31.07 | 40.06 | 102.47 | 260.43 | 1.08 | 0.12 | 50.91 | 60.36 |
DNMT1 | DNA (cytosine-5)-methyltransferase 1 | 19.32 | 18.12 | 25.10 | 15.49 | 12.21 | 7.08 | 8.25 | 41.24 | 60.53 |
SPARC | SPARC | 14,375.78 | 14,530.88 | 10,628.45 | 6504.71 | 4483.71 | 1286.8 | 1766.17 | 11,040.98 | 10,407.78 |
CDH13 | Cadherin-13 | 24.90 | 24.07 | 16.84 | 55.67 | 74.93 | 3.02 | 5.53 | 20.53 | 25.20 |
ADAMTS18 | A disintegrin and metalloproteinase with thrombospondin motifs 18 | 31.00 | 36.64 | 53.94 | 6.12 | 1.02 | 2.99 | 0.07 | 23.90 | 24.05 |
CBFA2T3 | Protein CBFA2T3 | 3.30 | 2.71 | 2.82 | 7.61 | 10.14 | 1.27 | 0.26 | 5.20 | 4.30 |
WNT11 | Protein Wnt-11 | 23.58 | 44.15 | 27.77 | 9.98 | 7.47 | 0.61 | 0.39 | 3.96 | 4.77 |
UCHL1 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | 55.84 | 78.46 | 186.74 | 20.74 | 15.65 | 5.82 | 2.91 | 24.44 | 26.96 |