Table 5 The obtained physicochemical properties.
From: Novel multi epitope-based vaccine against monkeypox virus: vaccinomic approach
Characteristics | Finding | Remark |
|---|---|---|
Number of amino acids | 275 | Suitable |
Molecular weight | 30.95 kDa | Average |
Theoretical pI | 9.82 | Basic |
Chemical formula | C1422H2134N386O383S5 | – |
Extinction coefficient (at 280 nm in H2O) | 58,790 M−1 cm−1 | – |
Estimated half-life (mammalian reticulocytes, in vitro) | 30 h | – |
Estimated half-life (yeast-cells, in vivo) | > 20 h | – |
Estimated half-life (E. coli, in vivo) | > 10 h | – |
Instability index of vaccine | 39.84 | Stable |
Aliphatic index of vaccine | 65.75 | Thermostable |
Grand average of hydropathicity (GRAVY) | − 0.467 | Hydrophilic |
