Table 1 Demographic and clinical characteristics of subjects with open-angle glaucoma.
Variables | MD > − 2 dB (H) | − 2 dB ≥ MD > − 6 dB (M) | − 6 dB ≥ MD > − 12 dB (L) | P-value | Post hoc | Total |
|---|---|---|---|---|---|---|
Subjects, n (%) | 35 (31.5) | 48 (43.2) | 28 (25.2) | 111 | ||
Age at baseline examination, y | 57.06 ± 12.18 | 56.52 ± 14.09 | 65.43 ± 13.90 | 0.015* | H, M < L | 59.01 ± 13.96 |
Male, n (%) | 19 (54.3) | 25 (52.1) | 12 (42.9) | 61 (55.0) | ||
Systemic factors | ||||||
Diabetes mellitus, n (%) | 7 (20.0) | 13 (27.1) | 7 (25.0) | 0.057* | 27 (24.3) | |
Hypertension, n (%) | 15 (42.9) | 19 (39.6) | 8 (28.6) | 0.158* | 42 (37.8) | |
Glaucoma | ||||||
Normal tension glaucoma, n (%) | 32 (91.4) | 39 (81.3) | 27 (96.4) | 98 (88.3) | ||
Primary open-angle glaucoma, n (%) | 3 (8.6) | 9 (18.7) | 1 (3.6) | 13 (11.7) | ||
Follow-up duration, y | 3.76 ± 0.39 | 3.51 ± 0.59 | 3.33 ± 0.67 | 0.009* | H > M > L | 3.54 ± 0.57 |
Follow-up OCT, n | 5.20 ± 0.96 | 5.63 ± 1.91 | 5.43 ± 1.60 | 0.485* | 5.44 ± 1.58 | |
Spherical equivalent (diopter) | − 0.52 ± 2.95 | − 1.29 ± 0.45 | − 1.26 ± 0.48 | 0.443* | − 0.87 ± 2.77 | |
IOP (mmHg) | 12.57 ± 0.47 | 13.38 ± 0.51 | 11.79 ± 0.58 | 0.109* | 12.19 ± 3.17 | |
Mean follow-up IOP (mmHg) | 11.89 ± 0.44 | 12.79 ± 11.98 | 11.36 ± 10.43 | 0.061* | 12.23 ± 2.63 | |
IOP fluctuation (mmHg) | 1.61 ± 0.13 | 1.74 ± 0.12 | 1.63 ± 0.12 | 0.694* | 1.70 ± 0.74 | |
Peak follow-up IOP (mmHg) | 13.77 ± 0.57 | 15.13 ± 0.50 | 13.54 ± 0.53 | 0.070* | 14.48 ± 3.30 | |
Axial length (mm) | 24.58 ± 0.27 | 24.10 ± 0.21 | 24.32 ± 0.36 | 0.382* | 24.19 ± 1.27 | |
Central corneal thickness (µm) | 521.63 ± 6.54 | 524.64 ± 5.38 | 522.65 ± 8.23 | 0.940* | 522.58 ± 36.79 | |
BMO area (mm2) | 2.32 ± 0.08 | 2.16 ± 0.06 | 2.25 ± 0.08 | 0.290* | 2.24 ± 0.43 | |
Optic disc hemorrhage, n (%) | 6 (17.1) | 7 (14.6) | 6 (21.4) | 0.855* | 19 (17.1) | |
Baseline visual field examination | ||||||
Mean deviation, dB | − 0.24 ± 0.93 | − 3.81 ± 1.03 | − 9.68 ± 2.66 | < 0.001* | H > M > L | − 4.22 ± 3.85 |
Pattern standard deviation, dB | 2.10 ± 0.88 | 4.15 ± 2.43 | 8.45 ± 3.49 | < 0.001* | H < M < L | 4.58 ± 3.30 |
