Figure 2 | Scientific Reports

Figure 2

From: Metabolic remodeling of pyrimidine synthesis pathway and serine synthesis pathway in human glioblastoma

Figure 2

Enriched molecular pathways with pathway overrepresentation analysis in 32 enzymes with 1.5-fold higher expressed and p-value < 0.05 and 67 enzymes with 0.67 (= 1/1.5)-fold lower expressed and p-value < 0.05 in the Positive compared to the Negative through the use of IMPaLA. The protein data from a gene by sample matrix is transformed to a gene-set by sample matrix with gene set variation analysis (R package gsva version 1.38.0). (a) Upregulated pathway analysis. (b) Downregulated pathway analysis.

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