Figure 1
From: Alloferon-1 ameliorates acute inflammatory responses in λ-carrageenan-induced paw edema in mice
The effect of alloferon-1 on the paw edema in carrageenan-induced mice. Mice were pretreated by intravenous injection with alloferon-1 (22 mg/kg body weight) for 6 h or aspirin (250 mg/kg body weight) for 2 h before subplantar injection of λ-carrageenan. Ctrl: saline solution; CGN: λ-carrageenan; AF: alloferon-1; ASA: aspirin. (A) a, Structure of alloferon-1; b, High pressure liquid chromatography (HPLC) detection of synthesized allofereron-1; c. mass spectrometry (MS) analysis of synthesized alloferon-1. (B) Appearances of paw edema in each group. (C) Measurements of the thickness of paw edema in mice using digital vernier caliper. Data are presented as the mean ± SEM (n = 5). *P < 0.05 were considered as significant difference compared to the control group.
