Figure 1 | Scientific Reports

Figure 1

From: DNA methylation landscapes from pig’s limbic structures underline regulatory mechanisms relevant for brain plasticity

Figure 1

Differentially methylated CpG sites in four tissues: the hypothalamus (Hypo), hippocampus (Hippo), amygdala (Amy), and adrenal gland (Agland) from German Landrace pigs. (a) Principal component analysis. (b) Profile plot61 depicting the methylation rate centered to: TSS of all genes in Sscrofa11.1 (top), TSS of genes with expression values in the mRNA profiling expression data from the same individuals (middle), and to annotated CGIs (bottom). Y-axis shows methylation level as methylation rate per CpG. (c) Feature annotation for 60,090 common meCpGs. The percentages for the promoter and gene body are split into sub-features. (d) Counts of significantly DMCs and DMRs, and annotated CGIs overlapping with the DMRs detected here.

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