Figure 4

Graphs of the statistical interaction effect between the DCA treatment as the first main factor and experimentally induced diabetic (DM) condition as the second main factor. Both factors had two levels: exposed to DCA (DCA ( +)) or not exposed to DCA (DCA ( −)), and presence of diabetes (coded DM ( +)) or absence of diabetes (DM ( −)). Combinations of these 2 × 2 levels define all four treatment groups (the design is termed a full factorial design in two levels): “DCA ( −) and DM ( −)“ stands for healthy control group (Control); “DCA ( −) and DM ( +)“ stands for diabetic group (DM); “DCA ( +) and DM ( −)“ stands for healthy dichloroacetate group (DCA); and “DCA ( +) and DM ( +)“ stands for diabetic-dichloroacetate group (DM + DCA).